Found 51 matching trials
Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL PHASE2 Based on the pediatric-inspired, PEG-L-asparaginase-intensified and MRD-dir...
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Department of Hematology, Nanfang Hospital
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Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia PHASE1 This study will test if adding ruxolitinib to standard multi-drug chemother...
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University of Chicago Medical Center
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Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL) PHASE1 H. Lee Moffitt Cancer Center and Research Institute will be the Sunshine Pr...
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Holtz Children's Hospital University of Miami Miller School of Medicine
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Ponatinib With Chemotherapy for Young Adults Ph Positive Acute Lymphoblastic Leukemia PHASE2 Evaluate the response (complete hematologic response \[CHR\], complete cyto...
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Hospital Germans Trias i Pujol
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Treatment With Combination Chemotherapy for Relapsed or Refractory Acute Lymphoblastic Leukemia PHASE1 Leukemia cells grow and divide fast and out of control. In normal cells, ce...
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St. Jude Children's Research Hospital
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Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome PHASE3 Randomized phase III trial to compare the effectiveness of different chemot...
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Children's Oncology Group
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EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL) PHASE1 An experimental drug called EZN-3042 targets survivin, a protein expressed ...
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Childrens Hospital Los Angeles
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Therapy for Pediatric Relapsed or Refractory Acute Lymphoblastic Leukemia PHASE2 The main purpose of this study is to find out how well participants with re...
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Rady Children's Hospital and Health Center
Treatments Being Tested
Etoposide, cytarabine, vincristine, dexamethasone methotrexate, teniposide, PEG-asparaginase mitoxantrone, cyclophosphamide, mercaptopurine, vinblastine L-asparaginase, erwinia asparaginase chemotherapy, intrathecal chemotherapy, steroid therapy Hematopoietic Stem Cell Transplant Natural Killer (NK) Cell Transplant Learn More & Join Trial
HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies PHASE1 HEM-iSMART is a master protocol which investigates multiple investigational...
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St. Anna Kinderspital
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Bortezomib-based Regimen for Refractory or Relapsed Acute Lymphoblastic Leukemia PHASE2 This is a interventional phase II study aiming to examine the complete resp...
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Instituto do Cancer do Estado de Sao Paulo
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